THIS ONE, FOR EXAMPLE; ARTICLE SHARED AS AN ABSTRACT FROM AROUND THE
WORLD ON THE PUBMED. MEDLINE HAS BIG NEWS RELEVENT TO THE HUMAN
BODY RENEWAL PROCESSES, NAMELY VIA ROUTE OF KIDNEY, HEART AND
TESTICLES - IN CASE OF RATS)
( all public - you pay or your institution subscribes only for the
full article, when author decides that the details are not suitable
for the public; many fast reaching scientists or I am suspecting CIA
discriminated, get the word out that way and can fast track most
valuable achievements that otherwise do not reach not only others but
USA)

"FormatSummary (text)Abstract (text)MEDLINE
Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2326-36. Epub 2010 May 31.

Cytoprotective effects of DL-alpha-lipoic acid or squalene on
cyclophosphamide-induced oxidative injury: an experimental study on
rat myocardium, testicles and urinary bladder.
Motawi TM, Sadik NA, Refaat A.

Biochemistry Department, Faculty of Pharmacy, Cairo University, Cairo,
Egypt.

Abstract
The present study aimed to evaluate the role of DL-alpha-lipoic acid
(LA) and squalene (SQ) on oxidative cardiac, testicular and urotoxic
damage induced by cyclophosphamide (CP). Male Wistar rats were divided
into four groups; three groups received a single intraperitoneal
injection of CP (200mg/kg BW) to induce toxicity, and two of these
groups received either LA (35 mg/kg BW) or SQ (0.4 ml/rat) orally 7
days before and 7 days after CP injection. A vehicle-treated control
group was also included. Oxidative damage was observed by decreased
serum total antioxidant capacity (TAC) level and abnormal alterations
in glutathione peroxidase (GPx) and glutathione reductase (GR)
activities, levels of glutathione (GSH), malondialdehyde (MDA), nitric
oxide (NO) and calcium (Ca(+2)) in the heart, testes and urinary
bladder of CP-administered rats. Cardiac marker enzyme activities;
creatine phosphokinase (CPK), lactate dehydrogenase (LDH), and
aspartate transaminase (AST) showed severe declines whereas testicular
markers; sorbitol dehydrogenase (SDH), gamma-glutamyl transferase
(gamma-GT), acid and alkaline phosphatases (ACP and ALP), serum
testosterone (T) level and haemoglobin (Hb) absorbance were abnormal.
Histopathological observations were also altered. These CP-induced
pathological alterations were attenuated by treatment with LA or SQ.
These findings highlight the efficacy of LA and SQ as cytoprotectants
in CP-induced toxicity.

Copyright (c) 2010 Elsevier Ltd. All rights reserved.
I DO NOT LIKE WHAT ELSEVIEW DOES AND OTHER TIMES I DO LIKE HERE,
PERHAPS POLICY ON HOW SOLID IS THE SCIENCE THAT GETS IN TO PRE-
PUBLICATION STAGE, UNCHECKED BY THE PUBLISHED CAN BE; OR WHERE ARE THE
CHECK POINT THAT FAST PUBLISHERS ARE TO BE WARRY OF CONSEQUENCES OF
FASIFYING DATA OR USING POLITICAL PROPAGANDA.
WHICHJ PROIPAGANDA TOO? - THE 2 ARTICLES BELOW EXPAND THE VIEW ON THE
PUBLIC OPPORTUNITY FOR THE HUMAN POTENTIAL AND ARE 'PROPAGANDA' THAT
WAY - MOTIVATE CERTAIN SOCIAL DIRECTION (  WOULD RTISK - ANTI-TACID
EUTANASIA); ARE THE POLITICAL PROPAGANDA? I AM PUSHING MY THOUGHT, AS
I THINK, THAT THERE ARE SUCH OR MIGHT BE
TOO, AND THAT THAT ASPECT CAN BE REDIRECTED WHEN PUBLIC THINKS CLEARER
- HALLO - THAT WILL BE WHEN NO ONE MORE CHIPIN A HEAD OR EVEN BODY!))

   ( the line listens to me to the pain;  do not do anything special I
am, more or less, myself only)
....

Unasuming journal that otherwise will only be reviewed by
toxicologists and environmental health specialists is crossreferenced
much better now via MEDLINE ( public part). What can we find out as
the member of te publ.ic not just specific profession: BIOCHEMISTRY
DEPARTMENT AT CAIRO UNI REPORTING THE ADVANCE OF ALFA-LIPOIC ACID THAT
WE KNOW AS THE FOOD SUPPLEMENT THAT WE KNOW FOR ANTI-FREE RADICALS
EFFECTS; ESPECIALLY BENEFICIAL FOR EYE FUNCTIONS, AND MOST SAAVY
TRACERS OF THE FOOD SUPLEMENTS USED IT IN ONE WAY OR THE OTHER, IN
FOOD OR FOOD SUPPLEMENTS; ( Biehner - forbid one more thing - not
buyng food suppluemnts on Americam Food Stamps)

 WHEN LOOKED AT IN THE LAB: WITH THE OTHER CHEMICAL COMPOUNDS THAT THE
PUBLIC DOES NOT STUDY, ARE MAKING THE IMPACT IN: THE CHAIN REACTION IN
VITAL ASPECT OF MAMMAL PHYSIOLOGY / quote:" "nitric oxide (NO) and
calcium (Ca(+2)) in the heart, testes and urinary bladder of CP-
administered rats."/

THE WHOLE SEQELLE OF THE BIO PROCESSES IS NOT ACCESIBLE TO ME; IF I
WERE TO USE THE THIS REFERENCE, I WOULD HAVE TO ASK AUTHORS FOR
CONSULTATION TO CHECEK WITH ME THE CONTEXTS AT WHICH I WILL APPLY THIS
FINDING IN MY RESEACH ( CONSULTINBG THE AUTHOR IS IN THE CULTURE EVEN
IN THE USA BUT WE USE IT NOT ENOUGH)

FROM THE STANDPOINT OF PROCESS, I WOULD LIKE TO UNDERSTAND THE
DISCOVERED CYCLING OF THE OXIDATIVE STRESS AND ITS RECOVERY BETTER.

AS A CONSUMER, I WANT TO FIND OUT IF THE 'squalene' IS SEPARAATE FOOD
SUPPLEMENT OF THE LIPOIC ACID OR ALFA- LIPOIC ACID AND ITS MARKET
SUPPLEMENTS ( I ALREDY KNOW EXCELLENT ONE - BARAGE OIL FOR WOMEN)
ALSO WILL ASK IF THE LIPOIC ACID THEY USE IS THE SAME IN THE FOOD
SUPPLEMENTS AND FOODS; MIND YOU, I WILL FIGURE SELF WHEN I AM BETTER
THAN THE RAT INPHYSIOLOGY ( SCIENTSTS ON THE WHOLE DO NOT ANSWER THESE
- THEY COULD TRY BUT THEY DO NOT YET)

I WOULD THAN SEARCH THE FOODS FOR LIPOIC ACID TRYING TO BREAK DOWN TO
THE TRUTH
( PEOPLE IN FOOD STORES AND EVEN 'VITAMINE SHOPPE' THOUGH THE BEST
THAN, OVESTATE THESE).

THAT SMALL ARTICLE DOES IT TO ME, AS  ACONSUMER AND THE DIFFERET
DISCIPLINE SCIENTIST.
THIS OPPORTUNITY WAS UNKNOWN BEFORE THE INTERNET; AND IF FOUND THE WAY
VIA MEDIA AND PUBLICATION LET SAY IN 'SCIENCE' , 'NATURE'  AND
'SCIENTIFIC AMERICAN' ONTHE NEWSTAND FIRST IN THE MORNING STILL( MEANT
TO BE MORE POPULAR THAT THE SPECIALIZED SCIENCE MAGAZINES), TAHT WILL
BE MUCH SLOWR PROCESS FOR ME TO FIND OUT HOW THAT FOOD SUPPLEMENT
OPERATES.

NOW AFTER THESE THOGHTS, I WANT TO ASK LOTS OF QUESTIONS:

1. SINCE THESE ANTIOXIDANTS IN THE CELL MAKE CHANGE FOR THE RENEWAL OF
THE ESSENTIAL HUMAN CLEANING AND REVOWING FUNCTION, I WANT MORE ( I
KNOW PRIVATELY THAT MY KIDNEYS, HEART AND EVEN SEX ORGANS SELF RENEW).
IS THERE ANYTHING WRONG WITH FINDING HOW IT DOES? APPARENTLY NOT

2. CULTURAL CHANGE NEEDED - ONLY FEW AND REALLY HIPED UP SCIENTISTS
DOCTORS IN USA WOULD ALLOW SELF DISCUSSION WITH THE PATIENT ON HOW
THIS MECHANISM GETS THROUGHT THE BODY; MIND YOU ,WOULD HAVE TO READ
AND UNDERSTAND APLLICATIONS.
 THE BEST DOCTORS DO AND THEY DO PULL THE RELEVANT INFO OF THE
INTERNET FOR THE PATIENT; SHOW WHERE TO LOOK FOR MORE.

BUT HOW MANY? WHAT ABOUT EDUCATIONAL ASPECT OF MEDICINE. IT IS LEFT TO
NURSES FOR THE MOST PART?. DO NURSES EVEN IN NEUROSCIENCES STUDY AS
MUCH NEW PHISIOLOGICAL BIOCHEMISTRY, AS NEEDED TO FULLY ANSWER MY
QUESTIONS ? NO.

3. WHAT THE SOLUTION?

   * APPREACIATE THE NOVELTY INNOVATIVE DOCTORS AS DESERVED ( DR
OBAMA
     FREE ZONNE FOR NOW)

   * DO NOT PESTERIZE THE SCIENCE INFO AS IT IS THIS DAYS IN THE
OPPOSITE OF THIS PROCESS HERE ,HOW THE ABSTRACT CAN BE A WINDOW TO THE
APPLICATIONS BUT PROFESSIONALLY INFORMATIVE ( IN OTHER CASE  IT GEST
TO BE SENSATIONAL STATEMENT ; WE ALREDY USE LIPOIC ACID - SO NO ADDED
EFFECTS YET THAT WAY)

    (HACJERS ARE CRAZY!  CAN NO BREAD)


   * HAVE PROFESSIOANAL INTERNET FILES PROPERLY LABELLED AND ACCESS BY
ASSOCIATION TO THE PROFESSIOANLS COMMUNITIES ( IT IS LIKE THAT NOW ,
BUT WHAT IS MISSING IS THE SENSE WHERE IS THE BOUNDERY LINE BETWEEN
PUBLIC AND PROFESSIONAL USE OF INFORMATION, ESPECIALLY SINCE THE
'BRITISH INVASION')

  THEY HAVE IT ON THE DESK IN USA SENATE BUT COUGHT SELF IN THE
VICIOUS CIRLCE - CUT THE MEDICARE, WHIEL TAHT IS ARTIFICIAL PROBLEM;
MEDICARE IS ABSOLUTE NECESSITY AND RESPONSIBILITY OF THE GOVERMENT -
IF USA CITIzENS WILL GO TO RETIRE AROUND THE WORLD
( THAT SI VERY REAL TOO AS MANY PEOPLE JUST DREAM ABOUT THAT HAVING
FAMILIES ALSWHERE, WHEN SO UNFROIENDLY HERE NPT ALL IMMIGRANBTS GOT IN
HERE FOR BETETR HOME BEACUSE HOME AS 'HOME' IS ELSWHERE).  USA
FUNCTION IN CARING FOR OWN IS GIVEN UP AND DAMAGES ARE NOT ONLY IN
PUBLIC USA IMAGE -

WHAT IF THESE PEOPLE RECOVER ABROAD FOR THE LONG RUN ? WHAT ABOUT THE
AMOUNT OF INFORMATION BIEHNER CAN STILL GET FOR SELF FROM THE WISDOM
OF
 PEOPLE ON THE MEDICARE! FRENCH THAT BE.


  *OTHER MEASURES

NEXT ARTICLE SOMEHOW EXEMPLIFYING IT TOGETHER WITH THE ETHICS,
/THAT AT TIMES ARE STILL MISSING IN THE INTERNET CULTURE, BUT ALSO IS
WITHIN
THE NEW LINES WHERE THE ETHICAL DILEMMAS ARE RESOLVED):

 ( THEY BOTHER MI TOO MUCH ON LINE - IT IS SPANISH ARTICLE ON PUB MED
THAT SHOWS HOW MEN RECOVER HEART ATTACK REGARDLES OF NO HOPE
EXPECTATION AND HOW THE MEDICAL COMMUNITY WAS WILLING TO SHARE THE
THOUGHT PROCES MAKING DECISIONS HOW TO DEFOBRILATE THE DHEART  IT IS
FOR PUBLIC - ALL INSTITUTIONS AND POLICE VEHICLES HAVE DEFIBLIRATORS;
IS THERE A ROOM FOR MORE UNDERSTNDING FROM THE STANDPOINT
OF PUBLIC EDUCATION WHAT TO DO ON THE WAY TO HOSPIATLA; ALSO CROSSO
PROFESSIONALLY)